How prosecutors can prove Brian Walshe murdered his wife Ana without finding her body

Ana Walshe, the missing Massachusetts mother who vanished on January 1, is now presumed dead - despite police never finding her body. 

Her husband Brian is in custody awaiting his next court date on charges of first degree murder. 

So far, he has pleaded not guilty, despite a mounting pile of incriminating evidence such as gruesome Google searches and dumpsters full of DNA. 

Here, DailyMail.com breaks down everything you need to know about the criminal case - and how a once-loving husband reached breaking point.