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So that's why Labradors get so fat! Scientists discover a genetic mutation in a quarter of all dogs that hard-wires them for obesity

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With their friendly and outgoing nature, it comes as no surprise that Labradors are some of the most popular dogs around the world. 

But Labradors are known to pile on the pounds - and now scientists think they know why. 

A genetic mutation in a quarter of Labradors hard-wires them for obesity, a study has found.

Around 25 per cent of Labradors face a 'double whammy' of feeling hungry all the time and burning fewer calories due to a genetic quirk, research suggests.

Experts say this combination drives obesity and means dog owners should be particularly strict when feeding and exercising their dogs to keep them slim.

With their friendly and outgoing nature, it comes as no surprise that Labradors are some of the most popular dog breeds around the world. But Labradors are known to pile on the pounds - and now scientists think they know why (stock image)

With their friendly and outgoing nature, it comes as no surprise that Labradors are some of the most popular dog breeds around the world. But Labradors are known to pile on the pounds - and now scientists think they know why (stock image)

The mutation is in a gene called POMC, which plays a key role in hunger and energy use, and changes how the dogs behave around food.

They do not need to eat more to feel full but they are hungrier in-between meals, the researchers found.

In addition, dogs with the mutation were found to use around 25 per cent less energy when resting than dogs without it.

As a result, they do not need to eat as many calories to maintain a healthy body weight.

Apart from Labradors, two-thirds of flat-coated retriever dogs also have the mutation, the team said.

Dr Eleanor Raffan, a researcher in the University of Cambridge's Department of Physiology, Development and Neuroscience, who led the study, said: 'We found that a mutation in the POMC gene seems to make dogs hungrier.

'Affected dogs tend to overeat because they get hungry between meals more quickly than dogs without the mutation.

'All owners of Labradors and flat-coated retrievers need to watch what they're feeding these highly food-motivated dogs, to keep them a healthy weight.

'But dogs with this genetic mutation face a double whammy: they not only want to eat more, but also need fewer calories because they're not burning them off as fast.'

The new study found the mutation changes how the dogs behave around food. They do not need to eat more to feel full, but they are hungrier in between meals, the researchers found

The new study found the mutation changes how the dogs behave around food. They do not need to eat more to feel full, but they are hungrier in between meals, the researchers found

READ MORE: The UK's most popular breeds of PUPPIES – so is your pooch on the list? 

Among UK puppies, general crossbreeds were found to be the most popular

Among UK puppies, general crossbreeds were found to be the most popular

The study, published in Science Advances, found that the gene mutation altered a pathway in the dogs' brains associated with body weight regulation.

The mutation triggers a starvation signal that tells their body to increase food intake and conserve energy, despite this being unnecessary.

Dr Raffan said: 'People are often rude about the owners of fat dogs, blaming them for not properly managing their dogs' diet and exercise.

'But we've shown that Labradors with this genetic mutation are looking for food all the time, trying to increase their energy intake. It's very difficult to keep these dogs slim, but it can be done.'

The researchers suggest owners can keep their retrievers distracted from this constant hunger by spreading out each daily food ration.

This could be done through using puzzle feeders or scattering the food around the garden so it takes longer to eat.

In the study, 87 adult pet Labrador dogs – all a healthy weight or moderately overweight – took part in several tests including the sausage in a box test.

They were first given a can of dog food every 20 minutes until they chose not to eat any more.

All of the pets ate a lot of food, but the dogs with the gene mutation did not eat more than those without it.

This showed that they all feel full with a similar amount of food.

On a different day, the dogs were fed a standard amount of breakfast, and three hours later they were offered a sausage in a clear plastic box and their behaviour was recorded.

The dogs could see and smell the sausage, but could not eat it.

Researchers found that dogs with the mutation tried significantly harder to get the sausage from the box than dogs without it, indicating greater hunger.

The dogs then slept in a special chamber that measured the gases they breathed out.

This revealed that the animals with the mutation burn around 25 per cent fewer calories than dogs without it.

Researchers say the new findings are consistent with reports of extreme hunger in humans with POMC mutations, who tend to become obese at an early age and develop a host of clinical problems as a result.

IS DOG INTELLIGENCE AKIN TO HUMAN INTELLIGENCE?

Dogs' abilities to learn are varied, much like humans' abilities, according to WebMD.

Dogs that were bred in order to hunt, retrieve or herd are faster learners because they are inherently quicker on their feet.

Similarly, dogs bred to guard livestock or track scents are usually slower.

A new study has found that mental deterioration among older dogs can be staved off if the dogs complete brain teasers on a touch screen (file photo)

A new study has found that mental deterioration among older dogs can be staved off if the dogs complete brain teasers on a touch screen (file photo)

The key in training your dog, WebMD says, comes down to knowing what your dog was bred to accomplish.

However, all dogs can be trained to follow simple commands, according to trainers.

WebMD reports that the following are the most naturally intelligent dog breeds:

  1. Border Collie
  2. Poodle
  3. German Shepherd
  4. Golden Retriever
  5. Doberman Pinscher
  6. Shetland Sheepdog
  7. Labrador Retriever
  8. Papillon
  9. Rottweiler
  10. Australian Cattle Dog 

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