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Weight loss influencer Lexi Reed, 33, who nearly DIED after suffering multiple organ failure that left her in a coma proudly reveals her staggering transformation after shedding 100LBS amid recovery from rare blood disease

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Weight loss influencer Lexi Reed has showcased her taunt figure after she dropped 100 pounds following her battle with calciphylaxis, which left her suffering from kidney failure and in a medically-induced coma. 

The 33-year-old from Indiana - who shot to fame in 2016 after documenting her 312-pound weight loss - has revealed she has shed off 100 pounds while in remission for her rare disease, in which calcium accumulates in small blood vessels of the fat and skin tissues and causes blood clots. 

She candidly opened up about her weight loss issues as well as her diagnosis in an Instagram post - adding that her life has been turned 'upside down.' 

Lexi boasted off her weight loss win on social media as she shared that she was terrified she wouldn't 'survive' before noting that she's so proud of herself for finding 'the strength' to fight, despite the 'odds being stacked against [her]'. 

Weight loss influencer Lexi Reed (seen before) has showcased her taunt figure after she dropped 100 pounds
Weight loss influencer Lexi Reed (seen after) has showcased her taunt figure after she dropped 100 pounds

Weight loss influencer Lexi Reed (seen left before and right after weight loss) has showcased her taunt figure after she dropped 100 pounds following her battle with calciphylaxis

The 33-year-old from Indiana - who shot to fame after documenting her 312-pound weight loss - has revealed she has shed off 100 pounds while in remission for her rare disease
Lexi went from 485 pounds (seen left) to 173 pounds in two years after overhauling her diet and starting a gym routine
Lexi went from 485 pounds to 173 pounds (seen) in two years after overhauling her diet and starting a gym routine

The 33-year-old from Indiana - who shot to fame after documenting her 312-pound weight loss - has revealed she has shed off 100 pounds while in remission for her rare disease 

She candidly opened up about her weight loss issues two years after being hospitalized and put in a medically-induced coma

She candidly opened up about her weight loss issues two years after being hospitalized and put in a medically-induced coma 

She wrote in the Instagram post: 'Remission, 100lbs, + my battle with Calciphylaxis - a rare disease that I was diagnosed with that completely turned my life upside down & made me question how strong that I truly was. 

'With personally having 30+ painful open wounds, and calciphylaxis having a mortality rate of over 80% due to infection (the leading cause of death), I was scared I wasn't going to survive.' 

She showed off her 100-pound weight loss in a mirror selfie and explained that she has been fighting hard to stay alive. 

Last year, Lexi underwent 59 weeks of treatment for the wounds that covered her body.

Now, she shared that she was able to overcome her 'pain' and 'fear.' 

'However, through the pain & through the fear, I found my strength to live & heal was more powerful than focusing on the odds stacked against me and I fought as hard as I could to survive one of the hardest battles of my life. 

'This picture shows more than just the weight I lost, but taking back the fight to live, healing & refusing to take life for granted. 

'Sometimes life with knock us down and make us question how strong that we truly are, but what matters most is not giving up despite what we face or the fear - start today!' the weight loss influencer 

Lexi boasted off her weight loss win on social media as she shared that she was terrified she wouldn't 'survive' but is so proud of herself for finding 'the strength' but fight against the odds

Lexi boasted off her weight loss win on social media as she shared that she was terrified she wouldn't 'survive' but is so proud of herself for finding 'the strength' but fight against the odds

She showed off her 100-pound weight loss in a mirror selfie and explained that she has been fighting hard to stay alive

She showed off her 100-pound weight loss in a mirror selfie and explained that she has been fighting hard to stay alive

Lexi's extreme weight loss left her with excess skin on her stomach, arms, and legs
Lexi's extreme weight loss left her with excess skin on her stomach, arms, and legs

Lexi's extreme weight loss left her with excess skin on her stomach, arms, and legs 

She noted that she will 'never take the chance to move for granted.' 

Lexi started her weight loss journey in 2016 when she weighed 485 pounds. 

In 2022, she was admitted into the Intensive Care Unit (ICU) with an unexplained kidney failure and had to be put into a medically-induced coma.

She was put on a ventilator and forced into a medically-induced coma, which left her unable to walk.

She underwent dialysis and spent a significant amount of time in a wheelchair. 

Lexi's husband, Danny, revealed via Instagram that she had been hospitalized after she 'couldn't keep any food down' and started 'acting differently.'

'A few weeks ago Lexi kept getting sick and couldn't keep any food down,' he wrote at the time.

'She then started acting differently so I took her to the hospital where they admitted her into ICU, placed on a medically induced comma, on a ventilator, and [told] me that her organs started failing.

Lexi (pictured in 2021) has been chronicling the ups and downs of her weight loss journey on her Instagram page over the past eight years

Lexi (pictured in 2021) has been chronicling the ups and downs of her weight loss journey on her Instagram page over the past eight years 

In 2018, she underwent a nine-hour surgery to remove seven pounds of excess skin from her body with the intention of having more removed in the future

In 2018, she underwent a nine-hour surgery to remove seven pounds of excess skin from her body with the intention of having more removed in the future

In 2022, she was admitted into the Intensive Care Unit (ICU) with an unexplained kidney failure and had to be put into a medically-induced coma

In 2022, she was admitted into the Intensive Care Unit (ICU) with an unexplained kidney failure and had to be put into a medically-induced coma

'They also told me if I had waited its possible she could have died. She is currently in dialysis, can't walk, and working on recovery.

'Sadly we do not have insurance. Thank you all for your prayers they all mean so much to us and this will be a long hard battle part of her story but she is strong!'

He also wrote on a GoFundMe page started for Lexi - where they've raised more than $60,000 - that she is waiting to find out if she needs a kidney or liver transplant.

Lexi and Danny shot to fame in 2016 after their weight loss story went viral.

The couple, who said 'I do' in 2015, weighed a combined 765 pounds and gorged on a total of 8,000 calories a day before making a New Year's resolution to lose weight.

They traded fast food for home-cooked meals and started going to the gym five to six times a week. In two years, Lexi went from 485 pounds to 173 pounds, while Danny dropped 95 pounds from his 208-pound frame.

'We didn't have a meal plan, surgery, personal trainer, but what we did have was each other and the motivation within to work hard every single day,' she wrote in an inspiring Instagram post in 2017.

Lexi noted that they had no idea that six months into their resolution they would become a 'completely different couple.'

She was put on a ventilator and forced into a medically-induced coma, which left her unable to walk

She was put on a ventilator and forced into a medically-induced coma, which left her unable to walk

After documenting her 312-pound weight loss, she now has 1.2 million Instagram followers
After documenting her 312-pound weight loss, she now has 1.2 million Instagram followers

After documenting her 312-pound weight loss, she gained 1.2 million Instagram followers

Lexi and Danny shot to fame in 2016 after their weight loss story went viral
Lexi and Danny shot to fame in 2016 after their weight loss story went viral

Lexi and Danny shot to fame in 2016 after their weight loss story went viral

'We may have lost the weight but we have grown closer together. Pound by pound, step by step, day by day — we have transformed our lives and molded our bodies into the people we've always wanted to be,' she shared.

Lexi ended the post with a tribute to her husband, explaining that Danny has always loved and supported her no matter what her weight.

In 2018, she underwent a nine-hour surgery to remove seven pounds of excess skin from her body with the intention of having more removed in the future.

For the past eight years, Lexi has been chronicling the ups and downs of her weight loss journey on her Instagram page, which has been a source of inspiration for millions.

In September, she shared side-by-side photos of herself at her heaviest and now, explaining she gained back some of the weight she had lost during the COVID-19 pandemic.

'I'm still happy to be alive after fearing I'd miss 30 and I'll never go back to where I was,' she wrote. 'Start today!'

What is calciphylaxis? 

Calciphylaxis is a serious, uncommon disease in which calcium accumulates in small blood vessels of the fat and skin tissues.

Calciphylaxis causes blood clots, painful skin ulcers and may cause serious infections that can lead to death. People who have calciphylaxis usually have kidney failure and are on dialysis or have had a kidney transplant. The condition can also occur in people without kidney disease.

Symptoms: 

  • Large purple net-like patterns on skin
  • Deep, very painful lumps that ulcerate, creating open sores with black-brown crust that fails to heal — typically in skin areas with high fat content, such as the stomach and thigh, although they can occur anywhere
  • Infections from wounds that don't heal

Causes:

The exact cause of calciphylaxis is unknown, but recent studies have revealed that most people with the condition have abnormalities in blood-clotting factors. Blood-clotting factors are substances in your blood that help stop bleeding. These abnormalities can lead to small blood clots forming more often than they normally would.

Source:  Mayo Clinic

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