Christina Applegate, 52, tears up as she admits her MS has left her in constant and 'excruciating pain' - while revealing symptoms that first alerted her to debilitating condition she has been battling for SEVEN YEARS

Christina Applegate fought back tears as she opened up about how being diagnosed with multiple sclerosis has left her feeling 'really pissed' and 'angry' and admitted that living with debilitating disease can be 'very lonely'.

During an exclusive interview with Robin Roberts on Good Morning America, the 52-year-old actress became emotional as she spoke about 'living in hell' with the illness which which impacts the brain, spinal cord and optic nerves. 

Christina explained how her symptoms started 'in the early part of 2021' when she was filming the final season of hit Netflix show Dead To Me and told Robin: 'It was like literally just tingling in my toes and by the time we started shooting in the summer of that same year, I was being brought to set in a wheelchair, I couldn't walk that far.'

As her eyes filled with tears, Christina's voice broke as she continued: 'So I had to tell everybody because I needed help, I needed someone to help me stand, and I needed someone to help me get there and they were wonderful, but I probably had it for many, many years.'

Christina Applegate fought back tears as she opened up about how being diagnosed with multiple sclerosis during an exclusive interview on Good Morning America

The 52-year-old was joined by fellow actress Jamie-Lynn Sigler who was diagnosed with MS when she was just 20-years-old

Christina, pictured here in January 2023, often walks using a cane as the debilitating disease impacts the brain, spinal cord as well as the optic nerves

When Robin, 63, asked the mother-of-one how long she thinks she'd had MS for before being diagnosed, the Married... with Children star replied: 'Probably six or seven years, I think. I noticed, especially the first season, we'd be shooting and I would buckle, like my leg would buckle. 

'I really just kind of put it off as being tired or "I'm dehydrated", or "it's the weather", then nothing would happen for like months and I didn't pay attention, but when it hit this hard, I had to pay attention.'

Sitting alongside fellow actress Jamie Lynn Sigler, who was diagnosed with MS 22 years ago, Christina admitted that she's still in a grieving process as she adapts to the way her life is now. 

'It sucks, it's not my favorite disease,' she said before joking about her 2008 breast cancer diagnosis: 'I have had a couple. It's not my favorite one!  They call it the invisible disease. It can be very lonely because it's hard to explain to people... I'm in excruciating pain, but I'm just used to it now.'

Referring to 42-year-old Jamie-Lynn, Christina then said: 'She keeps me going because I'm the one who's like... I'm flipping the bird all day long at this thing and I'm angry, I'm really, really pissed. 

'You know, I was a dancer, a runner and all these things that I love, and a mom. And she's like, "okay I have you and you are going to be okay", and if not for her, I really honestly don't know.'

Jamie-Lynn was quick to praise Christina for helping her to deal with her own emotions and said: 'For so long, I have been celebrated for being the strong one and the positive one that it felt like I was not that if I would admit that some days were hard.

'But she has really pushed me to be able to say that because I thought I was letting people down if I would talk about how hard it was sometimes,' she added, before sharing her thoughts on a cure.

The blond star said living with MS can be 'very lonely' and admitted that it's left her feeling 'angry'

Jamie-Lynn gave Christina a big hug when she got upset as she explained she 'needed help' to get around

Christina revealed that she's probably had MS for six or seven years as her leg would 'buckle' when filming season one of Dead To Me alongside Linda Cardellini (left)

Christina admitted that she got 'so freaked out' when she made a surprise appearance at the Emmy Awards in January

'There's this little bit of hope that maybe one day we won't live with this, it's hard to let that go,' she admitted as Christina joked: 'Yeah I'm waiting, that's why I'm sleeping. I want someone to just wake me up when it's over. Just wake me up when we can be like, "you're good, thank you!"'

But despite her daily struggles, the Bad Moms star has launched a new podcast called MeSsy alongside Jamie-Lynn and said she feels like she can finally be herself and wants listeners to also feel seen and heard.

'I've been playing a character called Christina for 40 years, who I wanted everybody to think I was because it's easier, but this is kind of my coming out party.

'This is the person I have been this whole time because I was kind of putting on a little act for everybody for so long because I thought that was easier to be light, "be funny, be light, don't make people feel uncomfortable", and I don't care anymore so that's kind of what this is.'

Fans were delighted when Christina made a surprise appearance at the Emmy Awards in January, where she walked onstage using a cane, but she admitted to Robin that she got 'so freaked out' at the star-studded ceremony.

'I actually kind of blacked out,' she said. 'People said, "oh you were so funny", and I'm like, "I don't even know what I said". I don't know what I was doing, I got so freaked out that I didn't even know what was happening anymore.' 

When asked if she felt the love after making her appearance at the 75th Emmy Awards, she replied: 'I mean, yes, yes. I live kind of in hell... I'm not out a lot so this is like a little difficult just for my system, but yeah of course the support is wonderful and I'm really grateful.' 

Christina received a standing ovation on the night and decided to make light of the beautiful moment as she told the famous crowd: 'You're totally shaming with disability by standing up, it's fine!'

Christina pictured a the Dead To Me season one premiere in May 2019, a couple of years before her MS diagnosis

Christina revealed that it was her friend and former co-star Selma Blair who urged her to go and get tested for MS

Touching on that moment again with Robin, she said: 'I felt really beloved and it was a beautiful thing,' before making another joke adding: 'I'm just going to say this, that audience stood up for everybody!'

Christina also praised her friend and The Sweetest Thing co-star Selma Blair for encouraging her to go and get tested for MS. 

The Emmy Award winner recalled: 'She goes, "you need to be checked for MS" and I said, "no, really? The odds, the two of us o from the same movie? Come on, that doesn't happen!" [but] she knew. If not for her, it could have been way worse.'

Selma, 51, was diagnosed with MS in August 2018 and claimed in a 2023 interview that her symptoms had begun to manifest themselves when she was a child.