Tragedy as orphaned three-month-old baby succumbs to his injuries days after his Apple executive dad and film producer mom died with his brother, one, when elderly woman 78 crashed her Mercedes SUV into them at a San Francisco bus stop

The toddler who would have been left orphaned after his parents were killed alongside his older brother, 1, when the driver plowed into them as they waited at a bus stop in San Francisco to go on a family day out at the city zoo. 

The boy, named Caue, died Wednesday, the horror crash occurred on Saturday afternoon. His death was confirmed by area Supervisor Myrna Melgar who added that the child's injuries were so severe, he had been in hospice care. 

Melgar also said that the toddler's organs would be donated, reports The San Francisco Chronicle.  

Apple executive Diego Cardoso de Oliveira, 40, his wife, producer Matilde Ramos Pinto, 38, and their one-year-old son, Joaquin, were earlier pronounced dead following the incident.  

Mary Fong Lau, 78, was arrested Sunday on suspicion of vehicular manslaughter, driving the wrong way, driving at an unsafe speed and reckless driving. 

Lau was initially taken to the hospital for injuries and it remains unclear what caused her car to hop the curb, crash into a fire hydrant, pole and side of the local library.

Baby Caue, shown left alongside his brother, Joaquin, was pronounced dead three days after his other family members

Matilde Ramos Pinto, 38, and the couple's one-year-old son were tragically killed on Saturday as they waited for the for the bus in West Portal, in the Bay Area, on their way to the zoo

Diego Cardoso de Oliveira, 40, was also killed. The crash also left their infant son, about three months old, in critical condition (not pictured)

Matilde was taken to the hospital after the crash, while her husband and child died at the scene

Matilde was taken to the hospital after the crash, while her husband and child died at the scene. She died on Sunday in the hospital.

Other people waiting for the bus to arrive were also injured from the crash and received medical attention.

The family lived in the Mission District, a neighborhood in the Bay Area, and planned to spend a day at the zoo together for Diego and Matilde's wedding anniversary, friends said.

Diego, a creative director at Apple, was from Brazil and Matilde was a film and advertising producer from Portugal.

Loved ones have been leaving tributes on the couple's social media accounts.

'So sorry this happened to you and your family. Rooting for your baby's health,' read one comment on Diego's Instagram.

Another said: 'My dear dear Matilde. I am so heartbroken. I cannot believe this you were and are an angel in my life forever. I miss you.'

The crash site has since been covered with stuffed animals, flowers, candles, and a stroller with a heart-shaped cutout that reads: : 'Remembering the precious lives lost on March 16, 2024.'

Advocates from Walk San Francisco added three pairs of shoes in honor of the mother, father and child who were tragically lost.

Witnesses said that the toddler went flying in the air from the impact of the crash.

Diego, a creative director at Apple, was from Brazil and Matilde was a film and advertising producer from Portugal

The family lived in the Mission District, a neighborhood in the Bay Area, and planned to spend a day at the zoo together for Diego and Matilde's wedding anniversary

The crash site has since been covered with stuffed animals, flowers, candles and tributes

Another witness, Nikki Mashburn, told The San Francisco Chronicle that she heard the crash and that is sounded like 'an explosion.' She said that the victims suffered head injuries.

'When the paramedics showed up, you could tell … they didn’t know what to do first,' Mashburn said.

'The stroller was clearly destroyed. Yeah, so he was still strapped in there,' Johanna Dimayuga, a resident in the area told CBS News.

Gabriel Cinquepalm, another witness, said that he saw Lau after the crash as she got out of her vehicle with a look as if to say: 'What have I done?' and that she was screaming at the sky. 

San Francisco Mayor London Breed said on X, formerly Twitter, that she had visited the scene of the collision on Saturday. She called it 'heartbreaking.'

Walk San Francisco has planned a memorial for the family at 5pm on Monday at the crash site.

The aftermath of the horror crash is pictured above

'We are heartbroken and heartsick and horrified,' Jodie Medeiros, the executive director of the advocacy group said.

'This is one of the worst pedestrian tragedies to ever occur on San Francisco streets. It is almost beyond comprehension.'

Following the tragedy, the group and locals have voiced their concerns about the intersection of Ulloa Street and West Portal Avenue where the bus stop is located.

The group noted that around the intersection, there are multiple places where families and children frequent, like a library, schools and train stations.

'It's time to fundamentally rethink areas like where this crash occurred, where thousands of people walk and cross and wait every day,' Medeiros said.

This was the second child killed in the city in less than a year, as deadly crashes like these have surged and left residents uneasy.