Mayo Clinic doctor Connor Bowman began calling himself a 'widow' in steamy Bumble conversations just days before his pharmacist wife was found fatally poisoned after their open marriage turned deadly

 A Mayo Clinic doctor accused of killing his wife was already referring to himself as a 'widow' days before her murder, search warrants have shown.

Connor Bowman, 31,  is charged with first-degree murder in the death of his wife, Betty Bowman, this past August.

A 32-year-old pharmacist who had been in an open relationship with Bowman before her death, she was killed by a lethal dose of a drug meant to fight gout.

Warrants filed Tuesday show how Bowman conducted computer searches for lethal doses of the drug in the days before her death, and how he also frequented the dating site Bumble.

Witnesses who met Bowman through the app spoke to cops in Rochester, Minnesota, where the couple lived. Several said Bowman told them his wife had died at some point prior, offering a timeline ranging from two weeks earlier to a year.

Connor Bowman, 31, is charged with first-degree murder in the death of his wife, Betty Bowman, this past August.

A 32-year-old pharmacist who had been in an open relationship with Bowman before her death, she was killed by a lethal dose of a drug meant to fight gout

According to the warrant filed in Olmsted County District Court, he told one woman his wife died 'earlier in the summer' of listeria poisoning - a rare affliction brought on by a specific genus of bacteria that acts as a parasite.

Before that, he told the same woman he 'knew what he wanted in life', and that Betty 'would have wanted him to move on to be happy.'

In another exchange with a witness who he reportedly matched with nine days after his wife died in a Rochester hospital, Bowman brought up a large life insurance payout he was left as a result - a revelation the woman said she thought was strange.

Other conversations and statements received from other witnesses indicated Bowman was identifying himself as a widower days earlier as well - before Betty's August 20 death.

Another woman witness interviewed over the course of the investigation said Bowman told her his wife died of a morphine overdose a year prior, while a third said she met Connor Bowman through the site on September 5.

She told cops in Olmsted County how she confronted him after learning his wife died just two and half weeks earlier - before they eventually honed in on him as a suspect after finding the drug colchicine in her system.

The warrant, in turn, demands access to Bowman's electronic devices and his account on Bumble, as witnesses also said the suspect brought up the insurance payout from Betty's death as early as three days after her death.

Warrants filed Tuesday show how Bowman conducted computer searches for lethal doses of the drug in the days before her death, and how he also frequented the dating site Bumble

Witnesses who met Bowman through the app spoke to cops in Rochester, Minnesota , where the couple lived

Several said Bowman told them his wife had died at some point prior, offering a timeline ranging from two weeks earlier to a year

In an interview with DailyMail.com in January, Berry's friend and former bridesmaid Sarah Leeser (left) described the red flags that led her to grow suspicious about her best friend's death

The warrant also details the extensive access Bowman had to lethal drug databases available through the University of Kansas, where he worked years before and was still employed on an 'as needed' basis, cops said.  

In the days before Betty's death, Bowman searched the database for colchicine, as well as what the lethal dose would be for someone 120 pounds.

Betty,  an operating room pharmacist who worked with her husband at the world-class clinic in Rochester, weighed about the same, the warrant states.

Investigators added how they found nothing to suggest Bowman should have been investigating poisonings caused by the niche drug, which was later found in Betty's bloodstream.

She died four days after being rushed to a hospital in dire straits after ingesting the drug, despite not having gout or any other medical issue at the time. 

The warrant, meanwhile, recounts interviews with several of the couple's friends and colleagues, many of whom recalled a detached and indifferent reaction from Bowman following Betty's death.

Several also aired suspicions about the sudden and severe illness that claimed her life, recalling how healthy she was when they knew her. 

An expert on poisons, he is currently being held in the Olmsted County Adult Detention Center on a $2 million bond.

Also noted was Bowman objections to an autopsy, after he told officials such an undertaking would be merely a 'hunting expedition' that would turn up nothing, one witness said. The pair had reportedly been in an open relationship

Also noted was  Bowman objections to an autopsy, after he told officials such an undertaking would be merely a 'hunting expedition' that would turn up nothing, one witness said.

He was indicted by a grand jury months later, on January 4, for his alleged part in his wife's death. He was arrested in October.

In an interview with DailyMail.com carried out this past January, Berry's friend and former bridesmaid Sarah Leeser described the red flags that led her to grow suspicious about her death 

She revealed her friend was bisexual, and had dating two people at the time – a man and a woman – just before her death. She added how husband Bowman had recently become infatuated with new love interest, and Betty concerned about how serious they were getting.

'Betty didn't understand why he was so infatuated,' said Sarah, 32. 'They both saw different people. But there was something different about this girl. It was more like obsession.'

At one point, Connor and the woman 'broke up,' Sarah said. 'He was super depressed and wanted to be with her all the time.'

Sarah (pictured with the pair) revealed that while the couple had agreed to an open marriage, Betty had grown concerned over Connor's new romantic pursuit and his dishonest behavior 

Betty, who died on August 20, was also upset that her husband often lied about his activities and whereabouts, telling her he was at work when he was actually out on a date.

'It was the lying and keeping secrets that became a problem,' Sarah said.

But there were other factors threatening their marriage, including their views on children: Connor wanted to start a family. Betty didn't.

'Betty wasn't ready, Connor was,' Sarah said. 'That was part of the discussion close to the end.'

As Betty contemplated whether the marriage could be saved, Sarah said she and other friends offered her a place to live.

Still, amid the turmoil, Sarah said she had no concern Connor might harm her. She never knew him to be physically abusive.

She also didn't recognize red flags when Betty ended up in the hospital with a sudden illness, nor when Connor told her that Betty, a healthy woman, was suffering from Hemophagocytic lymphohistiocytosi (HLH), a rare disease causing her organs to shut down.

Sarah said she did find it disconcerting when Connor started talking about collecting $500,000 in life insurance, and began openly flaunting his relationship with another woman shortly after Betty's death. He is being held in Olmsted County on a $2 million bond

After Betty's death, she noted, she found it disconcerting when Connor started talking about collecting $500,000 in life insurance, and when he began openly flaunting his relationship with the new girlfriend. 

Just days after Betty's death, Sarah said, Connor invited his lover to join her and other mutual friends at a winery where she saw them smiling, kissing, and hugging. 

It wasn't until days later, when detectives reached out that Sarah grew suspicious and began to question everything that that happened before and after Betty's death.

An expert on poisons, Bowman is currently being held in the Olmsted County Adult Detention Center on a $2 million bond.

He is scheduled to appear in Olmsted County District Court June 11 for his next hearing.