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Inches wide from Ryan Christie! Alex Scott tried his luck as Bournemouth piled on the pressure and the ball rebounded back out.
Christie was the first to latch onto it and his effort - a dagger that swerved through the air - had Aaron Ramsdale scrambling.
Luckily for the goalkeeper, the effort fizzed the wrong side of the post.
Just before we get going again, here's some half-time reading.
Graham Potter was quizzed on the Manchester United job and wowed supporters with his tactical analysis on Monday Night Football.
He's also rocking a nice turtleneck tonight. Lovely.
Antoine Semenyo's on fire and Bournemouth have a third!
Jamie Carragher believes top clubs will be looking at the ace and judging by that, it's not hard to see why.
Semenyo danced his way into a yard of space on the far side of the box and picked his spot inside Aaron Ramsdale's far corner.
Absolutely brilliant.
Antoine Semenyo, take a bow.
Evanilson brought Bournemouth away on the counter-attack and Marcus Tavernier found Semenyo on the edge of the box.
The tricky forward ducked and weaved into space before teeing up Lewis Cook, the midfielder finding the net via a deflection.
Replays showed the final touch came off Dango Ouattara!
Russell Martin is looking a little gloomy down on the touchline.
Southampton started well and looked composed on the ball but they've been visibly shaken by the manner of Bournemouth's opener.
Marcus Tavernier and Evanilson reacted much quicker than the backline and those moments punish teams in the Premier League.
Plenty of life left in this one, though!
Crucial defending from Charlie Taylor. Southampton need to be very careful they don't find themselves down by two early doors.
Dango Ouattara was released down the right-hand side and his low cross looked destined to find a team-mate.
Taylor slid in at the near post and diverted behind.
All of a sudden, Bournemouth are bursting with energy and searching for a quickfire second goal. The home crowd has come to life.
Russell Martin wasn't impressed with the breakthrough, however. He believed the ball was rolling for the quick free-kick.
VAR can't get involved with restarts, remember.
There's the goal he's been looking for!
Bournemouth took a free-kick quickly and Marcus Tavernier caught the Saints backline sleeping with a gorgeous ball over the top.
Evanilson stretched and tucked beyond Aaron Ramsdale with aplomb, his first goal in the hosts' red and black.
The £40million record signing is off the mark.
Very smart feet from Aaron Ramsdale on his old stomping ground.
Southampton looked to play out from the back again but Evanilson was alive to the danger and closed the goalkeeper down.
Ramsdale shifted the ball out of his feet slightly and evaded the challenge. He then booted high up field.
Jamie Carragher believes Antoine Semenyo could be the subject of big-name interest if he continues his good form for Bournemouth.
The forward has taken to life in the Premier League quite brilliantly. It's worth keeping an eye on his movement this evening.
He's a player that the top teams will be looking at.
He's a real threat.
Bournemouth moved quickly to replace Dominic Solanke with Evanilson, a hulking £40million buy from Porto.
He is still to get off the mark for the club but has impressed so far.
Agonisingly, the ace missed a penalty in the defeat to Chelsea at Vitality Stadium and has come close to scoring numerous times.
Will he bag that elusive first goal tonight?
There will be no Andoni Iraola in Bournemouth's dugout tonight. He is serving a touchline ban after picking up three yellow cards this season.
The third came in the defeat by Liverpool last weekend.
It is disappointing, but we cannot change it.
They told me that, with yellow cards, you cannot appeal them. That is something that doesn't happen in Spain, over there you can do it.
I think they probably understand my side now, but they cannot accept any appeals for yellow cards.
Bournemouth got the edge over their south coast neighbours in their last Premier League meeting back in April 2023.
Marcus Tavernier struck in the second half to secure a 1-0 win at St Mary's. Southampton went on to finish rock bottom and were relegated.
The Cherries, meanwhile, finished five points clear of the drop zone.
Expect some brutal chants for Ryan Fraser from the home crowd.
He is not a popular man at Bournemouth after refusing to sign an extension to take him to the end of the Covid-extended season.
There were more than a few wry smiles when Fraser was then sent to Newcastle's U-21s by Eddie Howe - the coach he had disappointed.
Fraser is up for this one, however, and starts.
It is going to be a great challenge for us.
Graham Potter is a guest pundit on Monday Night Football this evening and he has been full of praise for Russell Martin and Southampton.
The style or how you do it is a way for the club to align in everything. There are no guarantees.
The how cannot be the most important thing.
The players and what attributes they have are most important.
He sees possession as a way to do that. He is a brave young coach and I'm really impressed.
Bournemouth boss Andoni Iraola, speaking to Sky Sports...
'It has been a difficult start as we had a tough schedule. Two losses against Chelsea and Liverpool, this game will be key for us.
'The team controlling the game is the one having the chances.
'You prefer to be on the ball and to dictate the game - but I prefer the chances to have the ball.
'We have to be careful.'